Qiu, Xing’s team published research in Organic Letters in 2019 | CAS: 51644-96-3

Some of the reported applications of tert-Butyl (5-aminopentyl)carbamate(cas: 51644-96-3) include: synthesis of of a supermacrocycle that self-assemble to form organic nanotubes., preparation of water-soluble unsymmetrical sulforhodamine fluorophores from monobrominated sulfoxanthene dye, synthesis of functionalized porphyrins as biocompatible carrier system for photodynamic therapy (PDT).Name: tert-Butyl (5-aminopentyl)carbamate

Name: tert-Butyl (5-aminopentyl)carbamateIn 2019 ,《Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction》 appeared in Organic Letters. The author of the article were Qiu, Xing; Sun, Ning; Kong, Ying; Li, Yan; Yang, Xiaobao; Jiang, Biao. The article conveys some information:

Using DIPEA as base in N-methyl-2-pyrrolidinone (NMP), lenalidomide underwent regioselective alkylation with bromoesters and Boc-protected bromoamines followed by deprotection to yield lenalidomide derivatives as a library of potential PROTAC reagents. One of the products was coupled to the known BET binding agent JQ1 to yield I; I degraded BET protein in cells and effectively inhibited cancer cell proliferation.tert-Butyl (5-aminopentyl)carbamate(cas: 51644-96-3Name: tert-Butyl (5-aminopentyl)carbamate) was used in this study.

Some of the reported applications of tert-Butyl (5-aminopentyl)carbamate(cas: 51644-96-3) include: synthesis of of a supermacrocycle that self-assemble to form organic nanotubes., preparation of water-soluble unsymmetrical sulforhodamine fluorophores from monobrominated sulfoxanthene dye, synthesis of functionalized porphyrins as biocompatible carrier system for photodynamic therapy (PDT).Name: tert-Butyl (5-aminopentyl)carbamate

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