《Enantioselective Alkynylation of Unstabilized Cyclic Iminium Ions》 was written by Guan, Weiye; Santana, Samantha O.; Liao, Jennie; Henninger, Kelci; Watson, Mary P.. HPLC of Formula: 623-47-2 And the article was included in ACS Catalysis in 2020. The article conveys some information:
An enantioselective copper-catalyzed alkynylation of unstabilized cyclic iminium ions has been developed. Whereas such alkynylations typically utilize pyridinium, quinolinium, and isoquinolinium intermediates, this method enables use of cyclic iminium ions unstabilized by resonance. With the use of a Lewis acid and copper catalyst, these iminium ions are generated in situ from readily available hemiaminal Me ethers and transformed into highly enantioenriched α-alkynylated cyclic amines. A variety of terminal alkynes can be incorporated in high yields and enantiomeric excesses.Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2) was used in this study.
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.HPLC of Formula: 623-47-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics