In 2019,Organic Letters included an article by Dai, Peng; Tan, Xin; Luo, Qian; Yu, Xiang; Zhang, Shuguang; Liu, Fang; Zhang, Wei-Hua. HPLC of Formula: 623-47-2. The article was titled 《Synthesis of 3-Acyl-isoxazoles and Δ2-Isoxazolines from Methyl Ketones, Alkynes or Alkenes, and tert-Butyl Nitrite via a Csp3-H Radical Functionalization/Cycloaddition Cascade》. The information in the text is summarized as follows:
A novel metal-free tandem Csp3-H bond functionalization of ketones and 1,3-dipolar cycloaddition was developed. An efficient approach to a variety of oxazole and isoxazoline derivatives is demonstrated using the 1,3-dipolar cycloaddition of alkynes and alkenes to nitrile oxides generated by reactions of Me ketones with tert-Bu nitrite. This new protocol provides access to a variety of isoxazolines with diverse functionalities. An isoxazole generated in this way has significant antifungal activity. In the experimental materials used by the author, we found Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2)
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.HPLC of Formula: 623-47-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics