In 1967,Tetrahedron included an article by Baumann, Helmut; Franklin, Norman C.; Moehrle, Hans. Related Products of 936-03-8. The article was titled 《Configurations and conformations of 2-carboxycyclopentanols and the corresponding methyl and ethyl esters》. The information in the text is summarized as follows:
The N.M.R. spectra of cis- and trans-2-carboxycyclopentanol and the corresponding methyl and ethyl esters were measured, and from the chem. shift of the proton adjacent to the OH group and the band width of this signal, it was possible to assign the configurations of these pairs of isomers. The difference in chem. shift for this proton in the two isomers was considerably smaller than that found in the corresponding cyclohexane derivatives, a pair of which were measured. Thus, only when the compounds are extremely pure is it possible to assign the configurations in this way. The most stable conformations of trans-2-carboxycyclopentanol are I, II, and III. In the experiment, the researchers used Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8Related Products of 936-03-8)
Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Related Products of 936-03-8 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics