Zhou, Zheng-Xin; Li, Jia-Wei; Wang, Liang-Neng; Li, Ming; Liu, Yue-Jin; Zeng, Ming-Hua published an article in 2021. The article was titled 《Cooperative Ligand-Promoted P(III)-Directed Ruthenium-Catalyzed Remote Meta-C-H Alkylation of Tertiary Phosphines》, and you may find the article in Organic Letters.Reference of Ethyl 2-methyl-3-oxobutanoate The information in the text is summarized as follows:
Herein, the authors disclose a Ru-catalyzed meta-selective C-H activation of phosphines by using intrinsic P(III) as a directing group. 2,2,6,6-Tetramethylheptane-3,5-dione acts as the ligand and exhibits an excellent performance in boosting the meta-alkylation. The protocol allows an efficient and straightforward synthesis of meta-alkylated tertiary phosphines. Several meta-alkylated phosphines were evaluated for Pd-catalyzed Suzuki coupling and are superior to com. available ortho-substituted phosphines. The practicability of this methodol. is further demonstrated by the synthesis of difunctionalized phosphines. After reading the article, we found that the author used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Reference of Ethyl 2-methyl-3-oxobutanoate)
Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Reference of Ethyl 2-methyl-3-oxobutanoate
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