The author of 《In Situ Generation of Nitrile Oxides from NaCl-Oxone Oxidation of Various Aldoximes and Their 1,3-Dipolar Cycloaddition》 were Zhao, Guodong; Liang, Lixin; Wen, Chi Ho Ethan; Tong, Rongbiao. And the article was published in Organic Letters in 2019. Recommanded Product: Ethyl propiolate The author mentioned the following in the article:
Reported is a new green protocol for the efficient in situ generation of nitrile oxides through NaCl/Oxone oxidation of aldoximes and their dipolar cycloaddition The key feature is the use of a green chem. approach to address the substrate scope of aldoximes: broad scope (aliphatic, aromatic, and alkenyl aldoximes) without production of organic byproducts derived from oxidant and/or catalyst. Importantly, NaCl/Oxone-promoted three-component cycloaddition of aldehyde, hydroxylamine hydrochloride, and alkene was demonstrated to be competent (63-81%). The experimental process involved the reaction of Ethyl propiolate(cas: 623-47-2Recommanded Product: Ethyl propiolate)
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Recommanded Product: Ethyl propiolate
Referemce:
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