Srinivas, Dasari; Satyanarayana, Gedu published their research in Organic Letters in 2021. The article was titled 《Palladium Catalyzed Distal meta-C-H Functionalization of Arylacetic Acid Derivatives》.Safety of Benzyl acrylate The article contains the following contents:
Herein, meta-C-H olefination of phenylacetic acid derivatives I [R1 = R2 = Me, Et; R1 = H, R2 = Me; R1R2 = (CH2)4; R3 = H, 3-Me, 4-MeO, 4-Br, 3,4-Cl2, etc.] with alkenes R4CH:CHR5 (R4 = H, R5 = MeO2C, EtO2C, Me2NCO, MeSO2, 4-O2NC6H4, etc.; R4 = R5 = EtO2C; etc.) for the synthesis of arylacrylates and analogs II by tethering with a simple nitrile-based template through palladium catalysis has been presented. Notably, the versatility of the method has been evaluated with a wide range of phenylacetic acid derivatives for accomplishing the meta-olefination products in fair to excellent yields with outstanding selectivities under milder conditions. Significantly, the present strategy was successfully exemplified for the synthesis of drugs/natural product analogs, such as naproxen, ibuprofen, paracetamol, and cholesterol. The experimental process involved the reaction of Benzyl acrylate(cas: 2495-35-4Safety of Benzyl acrylate)
Benzyl acrylate(cas: 2495-35-4) has been used in preparation of high refractive index polyacrylates. Benzyl acrylate is used in the preparation of heptanoic acid benzyl ester. It is used to prepare polybenzylacrylate using azobisisobutyronitrile as initiator.Safety of Benzyl acrylate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics