Pu, Xiang; Dang, Qiu-Di; Yang, Lei; Zhang, Xia; Niu, Dawen published an article in 2022. The article was titled 《Doubly stereoconvergent construction of vicinal all-carbon quaternary and tertiary stereocenters by Cu/Mg-catalyzed propargylic substitution》, and you may find the article in Nature Communications.HPLC of Formula: 609-14-3 The information in the text is summarized as follows:
Here a doubly stereoconvergent, Cu/Mg-catalyzed asym. propargylic substitution reaction to convert simple starting materials to products with vicinal tertiary and all-carbon quaternary stereocenters in high yields and excellent diastereo- and enantioselectivities was reported. Both the nucleophiles and the electrophiles employed in this transformation were racemic. This reaction uses earth abundant metal catalysts, operates under ambient conditions and demonstrated broad substrate scope. The products of this reaction were functional group rich and synthetically versatile. Key to the success of this development was the devise of a Cu/Mg dual catalytic system and the identification of a bulky tridentate pyridinebisimidazoline (PyBim) ligand. The experimental part of the paper was very detailed, including the reaction process of Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3HPLC of Formula: 609-14-3)
Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.HPLC of Formula: 609-14-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics