Okada, Etsuji; Tsukushi, Norikado published an article in Heterocycles. The title of the article was 《A facile and convenient synthetic method for fluorine-containing 1H-pyrrolo[3,2-h]quinolines》.Recommanded Product: 59410-82-1 The author mentioned the following in the article:
Aromatic nucleophilic N-N exchange reaction of N,N-dimethyl-5,7-bis(trifluoroacetyl)-8-quinolylamine with some amino acid derivatives gave the corresponding N-[5,7-bis(trifluoroacetyl)-8-quinolyl]amino acid derivatives in excellent yields. Subsequent base-catalyzed cyclization afforded fluorine-containing 1H-pyrrolo[3,2-h]quinolines in high yields. After reading the article, we found that the author used H-Phg-OEt.HCl(cas: 59410-82-1Recommanded Product: 59410-82-1)
H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Recommanded Product: 59410-82-1 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics