Ning, Yongquan; Song, Qingmin; Sivaguru, Paramasivam; Wu, Lizuo; Anderson, Edward A.; Bi, Xihe published an article in 2022. The article was titled 《Ag-Catalyzed Insertion of Alkynyl Carbenes into C-C Bonds of β-Ketocarbonyls: A Formal C(sp2) Insertion》, and you may find the article in Organic Letters.SDS of cas: 403-33-8 The information in the text is summarized as follows:
Herein, a silver-catalyzed alkynyl carbene insertion into β-ketocarbonyls I (R1 = R3 = Me, Et, Ph, 4-t-BuC6H4, 3-thienyl, etc., R2 = H; R1 = Ph, R2 = H, R3 = Me, 4-F3CC6H4; R1 = R3 = Me, R2 = Me, Et, PhCH2; etc.) using alkynyl N-nosylhydrazones II [R4 = cyclopropyl, Cl(CH2)3, Ph, 3-MeOC6H4, 3,5-Cl2C6H3, 2-naphthyl, 1-cyclohexen-1-yl, etc.; Ns = 2-nitrophenylsulfonyl] as alkynyl carbene precursors, which provides access to trisubstituted allenyl ketones III, is reported. This reaction represents the first example of an alkynyl carbene insertion into a C-C σ bond, affording products homologated with an sp2 carbon center. The products are useful substrates for further transformations. Exptl. investigations and theor. calculations suggest the reaction proceeds through a stepwise enol cyclopropanation/retro-aldol pathway. In the experimental materials used by the author, we found Methyl 4-fluorobenzoate(cas: 403-33-8SDS of cas: 403-33-8)
Methyl 4-fluorobenzoate(cas: 403-33-8) is an organic fluorinated building block used for the synthesis of various pharmaceutical compounds. It can be used for the preparation of Blonanserin.SDS of cas: 403-33-8
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Ester – Wikipedia,
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