Liardo, Elisa; Rios-Lombardia, Nicolas; Moris, Francisco; Gonzalez-Sabin, Javier; Rebolledo, Francisca published an article in Organic Letters. The title of the article was 《Developing a Biocascade Process: Concurrent Ketone Reduction-Nitrile Hydrolysis of 2-Oxocycloalkanecarbonitriles》.Related Products of 936-03-8 The author mentioned the following in the article:
A stereoselective bioreduction of 2-oxocycloalkanecarbonitriles was concurrently coupled to a whole cell-catalyzed nitrile hydrolysis in one-pot. The first step, mediated by ketoreductases, involved a dynamic reductive kinetic resolution, which led to 2-hydroxycycloalkanenitriles in very high enantio- and diastereomeric ratios. Then, the simultaneous exposure to nitrile hydratase and amidase from whole cells of Rhodococcus rhodochrous provided the corresponding 2-hydroxycycloalkanecarboxylic acids with excellent overall yield and optical purity for the all-enzymic cascade. The results came from multiple reactions, including the reaction of Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8Related Products of 936-03-8)
Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Related Products of 936-03-8 Polyesters are important plastics, with monomers linked by ester moieties.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics