In 2022,Kong, Xianqiang; Chen, Yiyi; Chen, Xiaohui; Lu, Zheng-Xuan; Wang, Wei; Ni, Shao-Fei; Cao, Zhong-Yan published an article in Organic Letters. The title of the article was 《A Practically Unified Electrochemical Strategy for Ni-Catalyzed Decarboxylative Cross-Coupling of Aryl Trimethylammonium Salts》.Safety of Methyl 4-fluorobenzoate The author mentioned the following in the article:
By merging electrocatalysis and nickel catalysis, a unified strategy was successfully applied for preparing aryl ketones ArC(O)Ph [Ar = Ph, 4-ClC6H4, 4-MeC6H4, etc.], amides ArC(O)NR1R2 [Ar = Ph, 4-ClC6H4, 4-MeC6H4, etc.; R1 = R2 = Me, Et; R1R2 = CH2(CH2)2CH2, CH2CH2OCH2CH2], esters ArC(O)OR [Ar = Ph, 2-MeC6H4, 4-FC6H4, etc.; R = Me, Et] or aldehydes ArCHO [Ar = Ph, 4-MeC6H4, 4-PhC6H4, etc.] via decarboxylative cross-coupling of four types of α-oxocarboxylic acids and their derivatives with aryl trimethylammonium salts under mild conditions.Methyl 4-fluorobenzoate(cas: 403-33-8Safety of Methyl 4-fluorobenzoate) was used in this study.
Methyl 4-fluorobenzoate(cas: 403-33-8) can be used in the synthesis of trisubstituted imidazole derivatives containing a 4-fluorophenyl group, a pyrimidine ring, and a CN- or CONH2-substituted benzyl moiety.Safety of Methyl 4-fluorobenzoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics