In 1990,Tetrahedron included an article by Feenstra, R. W.; Stokkingreef, E. H. M.; Reichwein, A. M.; Lousberg, W. B. H.; Ottenheijm, H. C. J.; Kamphuis, J.; Boesten, W. H. J.; Schoemaker, H. E.; Meijer, E. M.. Synthetic Route of C10H14ClNO2. The article was titled 《Oxidative preparation of optically active N-hydroxy-α-amino acid amides》. The information in the text is summarized as follows:
Two routes are presented for the conversion of optically active α-amino acid amides into the title compounds One route (route A) features the formation of the Schiff bases 4-MeOC6H4CH:NCHRCONH2 (R = CHMe2, CH2CHMe2, Ph, CH2Ph, CH2CH2Ph), which are subsequently oxidized to the corresponding oxaziridines I. Route B is characterized by the formation of imidazolines II (R1 = Me, CH2CHMe2, Ph, CH2Ph; R2 = H), which are hydroxylated to hydroxy derivatives II (R2 = OH). Alcoholysis of I and II in the presence of H2NOH.HCl yields the title compounds in overall yields of 65-85% (route A) and 14-21% (route B).H-Phg-OEt.HCl(cas: 59410-82-1Synthetic Route of C10H14ClNO2) was used in this study.
H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters.Synthetic Route of C10H14ClNO2 They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics