Das, Amrita; Chatani, Naoto published an article in 2021. The article was titled 《Rh(I)- and Rh(II)-catalyzed C-H alkylation of benzylamines with alkenes and its application in flow chemistry》, and you may find the article in Chemical Science.Electric Literature of C10H10O2 The information in the text is summarized as follows:
The Rh-catalyzed C-H alkylation of benzylamines I (R = H, Me, F, CF3, etc.; R1 = H, Me, Cl, CF3; R2 = H, OMe, Cl; RR1 = -CH=CH-CH=CH-) and N-(thiophen-2-ylmethyl)picolinamide with alkenes CH2=CHR3 (R3 = ethoxycarbonyl, [(9Z)-octadec-9-en-1-yloxy]carbonyl, 2,3,4,5,6-pentafluorophenyl, etc.) using a picolinamide derivative II and Et 3-(2-(picolinamidomethyl)thiophen-3-yl)propanoate as a directing group is reported. Both Rh(I) and Rh(II) complexes can be used as active catalysts for this transformation. In addition, a flow set up was designed to successfully mimic this process under flow conditions. Several examples are presented under flow conditions and it was confirmed that a flow process is advantageous over a batch process. Deuterium labeling experiments were performed to elucidate the mechanism of the reaction, and the results indicated a possible carbene mechanism for this C-H alkylation process. In the experimental materials used by the author, we found Benzyl acrylate(cas: 2495-35-4Electric Literature of C10H10O2)
Benzyl acrylate(cas: 2495-35-4) is a reagent that can be used in the preparation of 2-(Phosphonomethyl)pentanedioic Acid, a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor. It can also be used in the preparation of high refractive index polyacrylates.Electric Literature of C10H10O2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics