Adriaens, E.; Verstraelen, S.; Desprez, B.; Alepee, N.; Abo, T.; Bagley, D.; Hibatallah, J.; Mewes, K. R.; Pfannenbecker, U.; Van Rompay, A. R. published their research in Toxicology In Vitro in 2021. The article was titled 《Overall performance of Bovine Corneal Opacity and Permeability (BCOP) Laser Light-Based Opacitometer (LLBO) test method with regard to solid and liquid chemicals testing》.Recommanded Product: 609-14-3 The article contains the following contents:
A prospective study of the Bovine Corneal Opacity and Permeability (BCOP) Laser Light-Based Opacitometer (LLBO) test method was conducted to evaluate its usefulness to identify chems. as inducing serious eye damage (Cat. 1) or chems. not requiring classification for eye irritation (No Cat.) applying United Nations Globally Harmonized System of Classification and Labeling of Chems. (UN GHS). The aim was to demonstrate the reproducibility of the BCOP LLBO protocol for liquids and solids and define its predictive capacity. Briefly, 145 chems. were simultaneously tested with BCOP LLBO and OP-KIT (OECD TG 437), one to two times in one laboratory When used to identify Cat. 1, the BCOP LLBO has a false neg. rate (FNR) of 24.1% (N = 56) compared to 34.8% (N = 56) for the BCOP OP-KIT, with a comparable false pos. rate (FPR, N = 89) of 18.5% and 20.8%, resp. When used to identify chems. not requiring classification (No Cat.) the BCOP LLBO and BCOP OP-KIT had a FNR (N = 104) of 6.2% and 7.2% and a FPR (N = 41) of 45.1% and 42.7%, resp. The OP-KIT and LLBO devices are interchangeable at no cost to data quality and reliability. The OP-KIT and LLBO devices are interchangeable at no cost to data quality and reliability. The performance of the LLBO is at least as good as the OP-KIT, both methods can be used to identify UN GHS Cat. 1 and UN GHS No Cat. chems. In the experimental materials used by the author, we found Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Recommanded Product: 609-14-3)
Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Recommanded Product: 609-14-3
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