ãDecreasing prevalence of specific anosmia to non-steroid odorants from childhood to adolescenceã?was published in Physiology & Behavior in 2020. These research results belong to Zou, Lai-Quan; Vogt, Olivia; Schriever, Valentin A.; Croy, Ilona; Schaal, Benoist; Hummel, Thomas. Application In Synthesis of Methyl Salicylate The article mentions the following:
Specific anosmia is defined as the inability to detect a particular odorant, despite a normal olfactory function. Previous studies reported sex-related difference in detection threshold to steroid odorants, like androstenone or androstadienone during adolescence, and boys showed an increased detection threshold with age. However, such investigations have not been performed for non-steroid odorants. Hence, the current study investigated sex- and age-related effects on the prevalence of specific anosmia in children/adolescents aged 5-14 years (n = 800) to non-steroid odorants. The detection thresholds of three non-steroid odorants (bacdanol, methylsalicylate, and 3-hydrox-2-methyl-4-pyrone) with different mol. weights were measured. Results indicate that the rate of specific anosmia for all three odorants decreases from childhood to adolescence. This decrease is independent of sex and is most pronounced for odorants with higher mol. weight compared to the odorant with lower mol. weight Thus, the development of basic olfactory functions for these three odorants continues until adolescence. The effect of mol. weight suggests that the locus of effect is at the periphery of the olfactory system, due to changes in either olfactory receptor expression patterns or perireceptor events. In the part of experimental materials, we found many familiar compounds, such as Methyl Salicylate(cas: 119-36-8Application In Synthesis of Methyl Salicylate)
Methyl Salicylate(cas: 119-36-8) has been used: as a component of clarifying solution for treating Mongolian gerbil cochlea intact for immunofluorescence analysis, as a plant elicitor to test its effect on reducing the whitefly population from tomato plants.Application In Synthesis of Methyl Salicylate
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