On December 15, 2020, Zhou, Tingting; Wan, Guofeng; Kong, Xueping; Li, Bao; Wu, Lixin published an article.Computed Properties of 2358-84-1 The title of the article was Biocompatible Polymer Nanocomposites Integrating Magnetic Polyoxomolybdates for Enhanced MRI and On-Site Activated Photothermal Properties. And the article contained the following:
This work reports the ionic composition of a PEGylated and chem. crosslinked polyethyleneimine with a gadolinium-coordinated polyoxomolybdate cluster, K17[Gd(P2Mo17O61)2], via electrostatic interaction. The prepared composites form nanoobjects with an average size of â?7 nm at dried state and maintain structural stability in aqueous solution While the biocompatibility on HeLa cells is demonstrated, the polymer-shielded multifunctional nanoplatform shows both the combined magnetic resonance imaging and redox-triggered photothermal conversion effect. As a contrast agent, the T1-weighed relaxivity reaches up to 22.77 mM-1 s-1. The photothermal conversion of the prepared composites can be aroused by yielding a broad near IR (NIR) adsorption through on-site reduction of the glutathione that is enriched in the tumor environment. The high efficiency â?1.0% under the irradiation of 808 nm NIR laser illustrates a distinct treatment capability according to cell counting Kit-8 assay while the obvious inhibition for the growth of tumor cells is observed The experimental process involved the reaction of Oxybis(ethane-2,1-diyl) bis(2-methylacrylate)(cas: 2358-84-1).Computed Properties of 2358-84-1
The Article related to mri tumor nanocomposite polyoxomolybdate, mri, magnetic polyoxomolybdate, nanocomposites, photothermal effects, redox-activation, Pharmaceuticals: Other and other aspects.Computed Properties of 2358-84-1
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