Tremblay, Thomas et al. published their research in Journal of Organic Chemistry in 2021 |CAS: 2873-29-2

The Article related to polyfluoroglycoside fluoroetoposide analog preparation anomeric hydroxyl group alkylation, Carbohydrates: Glycosides and other aspects.SDS of cas: 2873-29-2

On March 19, 2021, Tremblay, Thomas; St-Gelais, Jacob; Houde, Maxime; Giguere, Denis published an article.SDS of cas: 2873-29-2 The title of the article was Polyfluoroglycoside Synthesis via Simple Alkylation of an Anomeric Hydroxyl Group: Access to Fluoroetoposide Analogues. And the article contained the following:

In this work, we have developed a new approach for the synthesis of fluoroglycoside analogs. This strategy used a simple alkylation protocol and allowed the installation of a simple aglyconic alkane with the β configuration. Moreover, the glycosylation of fluorinated glucoside analogs with 4′-demethylepipodophyllotoxin furnished novel fluoroetoposide analogs. In these cases, the α anomers were formed as major products with an S configuration at the C-4 of the aglycon. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).SDS of cas: 2873-29-2

The Article related to polyfluoroglycoside fluoroetoposide analog preparation anomeric hydroxyl group alkylation, Carbohydrates: Glycosides and other aspects.SDS of cas: 2873-29-2

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