In 2022,Sarnes, Dustin M.; Jones, Peter G.; Lindel, Thomas published an article in Organic Letters. The title of the article was ãBiomimetic Synthesis of Cyanogramides B and Cã?Quality Control of H-Trp-OMe.HCl The author mentioned the following in the article:
Marinacarboline E and cyanogramides B and C from the marine-derived bacterium Actinoalloteichus cyanogriseus have been synthesized. The key step is the Baeyer-Villiger oxidation of marinacarboline E to a ketene aminal via O â?N acetyl migration, followed by addition of water or MeOH. Replacing the phenylethyl by a styryl side chain afforded dehydromarinacarboline E that was oxidized to a tetracyclic aminal. This study contributes to the chem. understanding of the enzymic conversions in the biosynthesis of the cyanogramides. In the part of experimental materials, we found many familiar compounds, such as H-Trp-OMe.HCl(cas: 7524-52-9Quality Control of H-Trp-OMe.HCl)
H-Trp-OMe.HCl(cas:7524-52-9) is one of amino acid derivatives. Amino acid derivatives represent an important category of skin penetration promoters. These compounds possess hydrophobic chains attached to an amino acid headgroup via a biodegradable ester bond. Due to the amphiphilic nature of these derivatives, it is possible for them to enter into the SC lipid barrier and significantly disorganize skin membrane lipids.Quality Control of H-Trp-OMe.HCl
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics