On January 6, 2020, Nawoj, Miroslaw; Grobelny, Artur; Mlynarski, Jacek published an article.Computed Properties of 2873-29-2 The title of the article was Macrolide Core Synthesis of Calysolin IX Using an Intramolecular Glycosylation Approach. And the article contained the following:
The utility of intramol. glycosylation for the synthesis of the 27-membered macrocyclic ring is highlighted in this first total synthesis of the most complex resin glycoside isolated to date – Calysolin IX. Oligosaccharide-containing macrolides core was effectively constructed by TfOH/NIS-promoted intramol. glycosylation of thioglycosyl donor. As the glycosidic bond must be created en route to target structure, we show that this unusual yet efficient approach can effectively reduce the number of steps in the total synthesis of complex natural macrolides. This attempt is documented as an efficient tool in the synthesis of gigantic macrolide rings thus proving their practical utility in the total synthesis of sugar-containing targets. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Computed Properties of 2873-29-2
The Article related to calysolin synthon preparation oligosaccharide intramol glycosylation macrocyclic resin glycoside, Carbohydrates: Oligosaccharides and other aspects.Computed Properties of 2873-29-2
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