ãMetal-Free Synthesis of Pyrazoles and Chromenopyrazoles from Hydrazones and Acetylenic Estersã?was published in ChemistrySelect in 2020. These research results belong to Bhaskaran, Rasmi P.; Janardhanan, Jith C.; Babu, Beneesh P.. Safety of Ethyl propiolate The article mentions the following:
An efficient, metal-free synthesis of pyrazoles and chromenopyrazoles from aldehyde hydrazones and acetylenic esters was developed. A library of mols. with diverse functional groups was synthesized using substituted hydrazones and alkynes, both sym. and unsym. ones. The derivatives were isolated in moderate to good yields. The experimental part of the paper was very detailed, including the reaction process of Ethyl propiolate(cas: 623-47-2Safety of Ethyl propiolate)
Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Safety of Ethyl propiolate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics