On February 12, 2020, Zhao, Huimin; Yang, Aiping; Zhang, Nan; Li, Shiyang; Yuan, Tianjie; Ding, Ning; Zhang, Siwang; Bao, Sheng; Wang, Chang; Zhang, Yinan; Wang, Xiachang; Hu, Lihong published an article.Formula: C5H10O3 The title of the article was Insecticidal Endostemonines A-J Produced by Endophytic Streptomyces from Stemona sessilifolia. And the article contained the following:
The discovery of new, safe, and effective pesticides is one of the main means for modern crop protection and parasitic disease control. During the search for new insecticidal secondary metabolites from endophytes in Stemona sessilifolia (a traditional Chinese medicine with a long history as an insecticide), 10 new insecticidal endostemonines A-J (1-10) were identified from an endophytic Streptomyces sp. BS-1. Their structures were determined by comprehensive spectroscopic anal. Endostemonines A-J represent the first reported naturally occurring pyrrole-2-carboxylic ester derivatives, which consisted of different fatty acid chains at the C-2 of pyrrole ring were produced by traditional Chinese medicine endophytic microbes. All new tested compounds exhibited strong lethal activity against Aphis gossypii (LC50 value range of 3.55-32.00 mg/L after 72 h). This research highlighted the discovery of pesticide natural products from insecticidal medicinal plant endophytes for the first time, paving a new pathway for the development of pest control. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Formula: C5H10O3
The Article related to endostemonine streptomyces endophyte stemona insecticide natural product, stemona sessilifolia, endophyte, endostemonine, insecticidal activity, secondary metabolite, Agrochemical Bioregulators: Microbial and other aspects.Formula: C5H10O3
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