On October 2, 2019, Tanaka, Keita; Ewing, William R.; Yu, Jin-Quan published an article.SDS of cas: 121129-31-5 The title of the article was Hemilabile Benzyl Ether Enables γ-C(sp3)-H Carbonylation and Olefination of Alcohols. And the article contained the following:
Pd-catalyzed C(sp3)-H activation of alc. typically shows β-selectivity due to the required distance between the chelating atom in the attached directing group and the targeted C-H bonds. Herein the authors report the design of a hemilabile directing group which exploits the chelation of a readily removable benzyl ether moiety to direct γ- or δ-C-H carbonylation and olefination of alcs. The utility of this approach is also demonstrated in the late-stage C-H functionalization of β-estradiol to rapidly prepare desired analogs that required multi-step syntheses with classical methods. The experimental process involved the reaction of Methyl 2-hydroxy-3,3-dimethylbutanoate(cas: 121129-31-5).SDS of cas: 121129-31-5
The Article related to benzyl ether alc carbonylation olefination palladium catalyst, General Organic Chemistry: Synthetic Methods and other aspects.SDS of cas: 121129-31-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics