Shenouda, Hannah et al. published their research in Organic Letters in 2019 |CAS: 3976-69-0

The Article related to primary alc preparation enantioselective, alkyl tosylate hydroxymethylation manganese catalyst, Aliphatic Compounds: Alcohols and Thiols and other aspects.Name: (R)-Methyl 3-hydroxybutanoate

On November 15, 2019, Shenouda, Hannah; Alexanian, Erik J. published an article.Name: (R)-Methyl 3-hydroxybutanoate The title of the article was Manganese-Catalyzed Stereospecific Hydroxymethylation of Alkyl Tosylates. And the article contained the following:

The development of a stereospecific hydroxymethylation of alkyl tosylates using an inexpensive, first-row catalyst is described. The transformation proceeds under mild conditions with low pressure to deliver homologated alcs. as products. Chiral, nonracemic β-branched primary alcs. are obtained with high enantiospecificity from easily accessed secondary alkyl substrates. Simple modification of the reaction system also permits access to α-d2 alcs. These studies use anionic metal carbonyl catalysis to access a synthetic equivalent of the challenging hydroxymethyl anion from carbon monoxide. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Name: (R)-Methyl 3-hydroxybutanoate

The Article related to primary alc preparation enantioselective, alkyl tosylate hydroxymethylation manganese catalyst, Aliphatic Compounds: Alcohols and Thiols and other aspects.Name: (R)-Methyl 3-hydroxybutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics