On April 20, 2000, Bjore, Annika; Granath, Anna-Karin published a patent.SDS of cas: 227940-70-7 The title of the patent was A dried or frozen pharmaceutical preparation containing a class III antiarrhythmic compound. And the patent contained the following:
The present invention relates to dried preparations containing a class III antiarrythmic compound in the form of crystalline or amorphous salt or any combination thereof, where the counterion is selected from pharmaceutically acceptable water-soluble organic or inorganic acids. The present invention also relates to frozen preparations containing a class III antiarrhythmic compound in the form of salt solution, where the counterion is selected from pharmaceutically acceptable water-soluble organic or inorganic acids. Preferred preparations contain a salt of the compound 3,7-diazabicyclo[3.3.1]-nonane-3-carboxylic acid 7-[(2S)-3-(4-cyanophenoxy)-2-hydroxypropyl]-1,1-dimethylethyl ester (Compound A). Further aspects of the present invention include salts of Compound A per se, processes for preparing the preparation, as well as use of the preparations for prophylaxis and/or treatment of cardiac arrhythmia. The experimental process involved the reaction of tert-Butyl 7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate(cas: 227940-70-7).SDS of cas: 227940-70-7
The Article related to antiarrhythmic diazabicyclononanecarboxylate freeze dried pharmaceutical, Pharmaceuticals: Formulation and Compounding and other aspects.SDS of cas: 227940-70-7
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics