Yang, Yong-Qing; Ji, Meng-Chen; Lu, Zheng; Jiang, Mao; Huang, Wei-Wei; He, Xue-Zhi published an article in 2016, the title of the article was Facile access to α,β-dehydroalanine and α,β-dehydroamino butyric acid derivatives from DL-serines and threonines.Recommanded Product: Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate And the article contains the following content:
Not only α,β-dehydroamino acids are important constituents for a number of bioactive peptides in nature, but also they are important building blocks for a variety of synthetic amino acids in organic synthesis. Methods to prepare dehydroamino acids have been reported extensively in the literature; however, efficient and convenient protocols are still required. Here, the authors report a convenient method to prepare dehydroalanine (ΔAla) and dehydroamino butyric acid (ΔAbu) derivatives derived from DL-serines and DL-threonines, resp. 4-Toluenesulfonyl chloride (TsCl) and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) were employed in this procedure, which carried out activation of hydroxyl group and β-elimination in one pot. Because it is convenient and easy to handle, this method will attract the attention of synthetic chemists. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Recommanded Product: Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate
The Article related to dehydroamino acid preparation beta elimination racemic serine threonine, Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Recommanded Product: Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate
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