On September 30, 2000, Hashimoto, Yoshiya; Nakamura, Masaaki published an article.Recommanded Product: 1985-51-9 The title of the article was Estrogenic activity of dental materials and bisphenol-A related chemicals in vitro. And the article contained the following:
Twenty-eight chems. used as dental materials and bisphenol-A related chems. were diluted with DMSO to concentrations ranging from 10-7 to 10-3M and tested for estrogenicity. Bisphenol-A (BPA), bisphenol-F (BPF) and bisphenol-A-bischloroformate (BPACF) showed estrogenic activity by using the yeast 2-hybrid system, and BPA, BPF, BPACF and bisphenol-S (BPS) showed estrogenic activity by using the fluorescence polarization system. However, none of the remaining chems. and none of the dental materials showed any activity at concentrations between 10-7 and 10-3M. Although BPA, BPF, BPACF, bisphenol-A-dimethacrylate and BPS showed estrogenic activity in the E-screen test, the remaining chems. did not. Thus, most of the chems. showed consistent results, either pos. or neg., by the three testing methods, while 2 compounds showed conflicting results. Further studies, together with in vivo and epidemiol. examinations, are required. Elucidation of the structure-activity relationships of these chems. is also needed to estimate the estrogenicity of a chem. from its structure. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Recommanded Product: 1985-51-9
The Article related to bisphenol a dental composite estrogen, endocrine disrupter bisphenol a dental composite, Pharmaceuticals: Prosthetics and Medical Goods and other aspects.Recommanded Product: 1985-51-9
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