On March 5, 2018, Brodzka, Anna; Koszelewski, Dominik; Zysk, Malgorzata; Ostaszewski, Ryszard published an article.Recommanded Product: 707-07-3 The title of the article was The mechanistic promiscuity of the enzymatic esterification of chiral carboxylic acids. And the article contained the following:
The studies on the enzymic kinetic resolution of 3-phenyl-4-pentenoic acid with various trialkyl orthoesters as alkoxy group donors are presented. The obtained results indicate that enantioselectivity of presented reaction is closely related to the alkoxy group donor structure. Based on critical anal. of the literature data and our own results we found that the previously recognized mechanism of such transformation is highly unlikely. In this paper we proposed a new revised mechanism explaining the role of alkoxy group donors. For trialkyl orthobenzoates excellent enzymic kinetic resolution of target substrate was achieved. The presented method is an unique example of an enzymic promiscuous activity toward esterification of carboxylic acids. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Recommanded Product: 707-07-3
The Article related to lipase catalysis carboxylic acid esterification chiral ester kinetic resolution, Enzymes: Kinetics-Mechanism-Enzyme and Coenzyme Models and other aspects.Recommanded Product: 707-07-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics