On January 1, 2017, Bernard, L.; Bourdeaux, D.; Pereira, B.; Azaroual, N.; Barthelemy, C.; Breysse, C.; Chennell, P.; Cueff, R.; Dine, T.; Eljezi, T.; Feutry, F.; Genay, S.; Kambia, N.; Lecoeur, M.; Masse, M.; Odou, P.; Radaniel, T.; Simon, N.; Vaccher, C.; Verlhac, C.; Yessad, M.; Decaudin, B.; Sautou, V. published an article.Name: Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate The title of the article was Analysis of plasticizers in PVC medical devices: Performance comparison of eight analytical methods. And the article contained the following:
A wide variety of medical devices (MDs) used in hospitals are made of flexible plasticized polyvinylchloride (PVC). Different plasticizers are present in variable amounts in the PVC matrix of the devices and can leach out into the infused solutions and may enter into contact with the patients. The ARMED1ARMED: Assessment and Risk Management of Medical Devices in Plasticized Polyvinylchloride. project aims to assess the migration of these plasticizers from medical devices and therefore the level of exposure in patients. For the first task of the project, eight methods were developed to directly detect and quantify the plasticizers in the PVC matrix of the MDs. We compared the overall performances of the anal. methods using standardized and validated criteria in order to provide the scientific community with the guidance and the tech. specifications of each method for the intended application. We have shown that routine rapid screening could be performed directly on the MDs using the FTIR technique, with cost-effective analyses. LC techniques may also be used, but with limits and only with individual quantification of the main plasticizers expected in the PVC matrix. GC techniques, especially GC-MS, are both more specific and more sensitive than other techniques. NMR is a robust and specific technique to precisely discriminate all plasticizers in a MD but is limited by its cost and its low ability to detect and quantify plasticizer contamination, e.g. by DEHP. All these results have been confirmed by a real test, called the ” blind test ” carried out on 10 MD samples. The experimental process involved the reaction of Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate(cas: 3319-31-1).Name: Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate
The Article related to plasticizer polyvinyl chloride medical device analysis method, analytical methods, comparison, medical devices, plasticizers, Pharmaceutical Analysis: Synthetic Organic Compounds and other aspects.Name: Tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate
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