On December 31, 2014, McEnaney, Patrick J.; Fitzgerald, Kelly J.; Zhang, Andrew X.; Douglass, Eugene F. Jr.; Shan, Weifang; Balog, Aaron; Kolesnikova, Mariya D.; Spiegel, David A. published an article.Recommanded Product: Bis(2,5-dioxopyrrolidin-1-yl) glutarate The title of the article was Chemically Synthesized Molecules with the Targeting and Effector Functions of Antibodies. And the article contained the following:
This article reports the design, synthesis, and evaluation of a novel class of mols. of intermediate size (approx. 7000 Da), which possess both the targeting and effector functions of antibodies. These compounds-called synthetic antibody mimics targeting prostate cancer (SyAM-Ps)-bind simultaneously to prostate-specific membrane antigen and Fc gamma receptor I, thus eliciting highly selective cancer cell phagocytosis. SyAMs have the potential to combine the advantages of both small-mol. and biol. therapies, and may address many drawbacks associated with available treatments for cancer and other diseases. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).Recommanded Product: Bis(2,5-dioxopyrrolidin-1-yl) glutarate
The Article related to antitumor neoplasm prostate specific membrane antigen, Pharmacology: Effects Of Neoplasm Inhibitors and Cytotoxic Agents and other aspects.Recommanded Product: Bis(2,5-dioxopyrrolidin-1-yl) glutarate
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