On July 31, 1992, Kessler, Horst; Wittmann, Valentin; Koeck, Matthias; Kottenhahn, Matthias published an article.Application In Synthesis of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate The title of the article was Synthesis of C-glycopeptides by radical addition of glycosyl bromides to dehydroalanine derivatives. And the article contained the following:
Radical addition of glycosyl bromides I (R1 = H, R2 = OAc, tetra-O-acetyl-β-D-galactopyranosyl; R1 = OAc, R2 = H) with urethane-protected dehydroalanine derivatives R3NHC(COR4):CH2 [R3 = 9-fluorenylmethoxycarbonyl (Fmoc), PhCH2O2C (Z), Me3CO2C (Boc), R4 = OCH2Ph; R3 = Fmoc, R4 = Phe-OCH2Ph, D-Phe-OCH2Ph; R3 = Z-Pro, R4 = Ala-OCH2Ph] in the presence of Bu3SnH and AIBN gave C-glycopeptides II as mixtures of stereoisomers at the amino acid chiral center. The stereochem. of the adducts was determined by conversion to lactone derivatives, e.g. III. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Application In Synthesis of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate
The Article related to radical addition glycosyl bromide dehydroalanine, stereochem addition glycosyl radical dehydroalanine, glycopeptide, Amino Acids, Peptides, and Proteins: Poly(Amino Acids) and Peptides and other aspects.Application In Synthesis of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate
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