On March 24, 2016, Cremonesi, Susanna; Luker, Tim; Semeraro, Teresa; Micheli, Fabrizio published a patent.Name: tert-Butyl 1-oxo-2,9-diazaspiro[5.5]undecane-9-carboxylate The title of the patent was Preparation of spirocyclic derivatives for the treatment and prevention of dopamine transporter-mediated diseases. And the patent contained the following:
The invention relates to preparation of spirocyclic derivs of formula I wherein R1, R2, R3, R4, R5, R6, R9, R10, Q, X, Y, Z, A, L, B, m, n and p are as defined in the disclosure, pharmaceutical compositions comprising such compounds; their use in therapy (for example in the treatment or prevention of a disease, disorder or condition ameliorated by inhibition of a dopamine transporter). The experimental process involved the reaction of tert-Butyl 1-oxo-2,9-diazaspiro[5.5]undecane-9-carboxylate(cas: 1198284-94-4).Name: tert-Butyl 1-oxo-2,9-diazaspiro[5.5]undecane-9-carboxylate
The Article related to spirocyclic derivative preparation dopamine transporter disease therapy prophylaxis, Heterocyclic Compounds (More Than One Hetero Atom): General and other aspects.Name: tert-Butyl 1-oxo-2,9-diazaspiro[5.5]undecane-9-carboxylate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics