Veena, Bacchu; Sharma, Gangavaram V. M. published an article in 2014, the title of the article was Stereoselective synthesis of macrosphelide I.Recommanded Product: (R)-Methyl 3-hydroxybutanoate And the article contains the following content:
An efficient total synthesis of (4R,7E,9R,10S,15R,16S)-9,15-dihydroxy-4,10,16-trimethyl-1,5,11-trioxacyclohexadec-7-ene-2,6,12-trione (macrosphelide I) has been achieved starting from com. available chiral materials, Et (S)-lactate and Me (R)-3-hydroxybutyrate. The synthesis of the target compound was carried out by a titanium(IV) promoted regioselective nucleophilic opening reaction of epoxy alc. with benzoic acid, Sharpless epoxidation, ring-closing metathesis and Yamaguchi esterification as key steps for the construction of the 16-membered macrotriolide. (2E,4S)-4-[(4-Methoxyphenyl)methoxy]-2-penten-1-ol was used as a starting material. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Recommanded Product: (R)-Methyl 3-hydroxybutanoate
The Article related to macrosphelide preparation total synthesis cytotoxic anticancer antitumor agent, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Recommanded Product: (R)-Methyl 3-hydroxybutanoate
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