Srinivas, Avula; Rao, Enugala Kalyan published an article in 2021, the title of the article was Synthesis and anticancer activity of triazole linked macrocycles and heterocycles.Category: esters-buliding-blocks And the article contains the following content:
Synthesis of macrocylic enones starting from alkyl ether and triazole as a linker was achieved using click reaction and intramol. aldol condensation. The newly synthesized macrocyclic enone was successfully utilized as a dipolarophile in 1,3-dipolar cycloaddition The dipoles generated from hydrazine hydrochloride, hydroxylamine and guanidine hydrochloride were reacted with macrocyclic enone to give a new class of spiro aminopyrimidines, Ph pyrazoles and isoxazoles grafted macrocycles in good yield. The structures of newly synthesized compounds were confirmed with IR, NMR and mass spectroscopy and evaluated for their anti cancer activity. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Category: esters-buliding-blocks
The Article related to triazole linked macrocycle spiro aminopyrimidine phenyl pyrazole isoxazole anticancer, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics