On June 15, 2018, Shimada, Kousei; Ohata, Yasuo; Kobayashi, Jun; Onishi, Yoshiyuki; Kawamura, Asuka; Domon, Yuki; Arakawa, Naohisa; Inoue, Tatsuya; Kitano, Yutaka; Matsuda, Fumihiko; Abe, Yuki; Deguchi, Tsuneo published an article.Recommanded Product: (R)-Methyl 3-hydroxybutanoate The title of the article was Alkylsulfanyl analogs as potent α2δ ligands. And the article contained the following:
The authors identified novel (3R, 5S)-3-aminomethyl-5-methanesulfanyl hexanoic acid (5a: DS75091588) and (3R, 5S)-3-aminomethyl-5-ethanesulfanyl hexanoic acid (6a: DS18430756) as sulfur-containing γ-amino acid derivatives that were useful for the treatment of neuropathic pain. These two compounds exhibited a potent analgesic effect in animal models of both type I diabetes and type II diabetes, and good pharmacokinetics. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Recommanded Product: (R)-Methyl 3-hydroxybutanoate
The Article related to alkylsulfanyl analog preparation alpha2delta calcium channel neuropathic pain analgesic, alkylsulfanyl, analgesic, diabetes, α(2)δ, γ-amino acid, Pharmacology: Effects Of Nervous System- and Behavior-Affecting Drugs and Neuromuscular Agents and other aspects.Recommanded Product: (R)-Methyl 3-hydroxybutanoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics