On July 5, 2018, Lundgren, Rylan; Moon, Patrick published a patent.Safety of Ethyl 2-(4-(trifluoromethoxy)phenyl)acetate The title of the patent was Oxidative coupling of aryl boron reagents with sp3-carbon nucleophiles, and ambient decarboxylative arylation of malonate half-esters via oxidative catalysis. And the patent contained the following:
Described herein are methods of oxidative coupling of aryl boron reagents with sp3-carbon nucleophiles, and ambient decarboxylative arylation of malonate half-esters via oxidative catalysis. A method for arylation of an sp3 carbon nucleophile, comprising: reacting (a) an arylboroxine or a compound Ar-B(OR)2, wherein R=alkyl; (b) an sp3-carbon nucleophile; (c) a copper based stoichiometric promoter, and (d) triethylamine; as well as a method for decarboxylative carbonyl α-arylation, comprising: reacting (1) an aryl coupling partner; (b) a carboxylic acid, and (c) a copper based catalyst, are claimed. Example compound I was prepared by decarboxylative arylation of monoethyl malonate with 3-iodophenyl neopentyl boronic ester. The experimental process involved the reaction of Ethyl 2-(4-(trifluoromethoxy)phenyl)acetate(cas: 1206550-93-7).Safety of Ethyl 2-(4-(trifluoromethoxy)phenyl)acetate
The Article related to oxidative coupling aryl boron reagent carbon nucleophile copper catalyst, decarboxylative arylation mono malonate ester oxidative catalysis, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Esters, Acyl Peroxides, Acyl Halides and other aspects.Safety of Ethyl 2-(4-(trifluoromethoxy)phenyl)acetate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics