Di Gioia, M. L.; Costanzo, P.; De Nino, A.; Maiuolo, L.; Nardi, M.; Olivito, F.; Procopio, A. published an article in 2017, the title of the article was Simple and efficient Fmoc removal in ionic liquid.Recommanded Product: 53838-27-0 And the article contains the following content:
A mild method for an efficient removal of the fluorenylmethoxycarbonyl (Fmoc) group in ionic liquid was developed. The combination of a weak base such as triethylamine and [Bmim][BF4] made the entire system more efficient for the cleavage at room temperature of various amines e.g. I and amino acid alkyl esters II [R1 = NH2, HNMe; R2 = Me, i-Pr, Ph, etc.; R3 = Me, t-Bu, CH2C6H5] short reaction times. The procedure worked well even in the case of N-Fmoc amino acids bearing acid-sensitive protecting groups and of N-alkylated amino acid alkyl esters, III, e.g. The solvent-free condition provided a complementary method for Fmoc deprotection in solution phase peptide synthesis and modern organic synthesis. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Recommanded Product: 53838-27-0
The Article related to acetyl alkyl ester green preparation, amine amino acid methyl ester preparation acetic anhydride acetylation, amino acid alkyl ester amine deprotection ionic liquid catalyst and other aspects.Recommanded Product: 53838-27-0
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics