Yao, Wang; Wang, Hao; Zeng, Jing; Wan, Qian published an article in 2021, the title of the article was Practical synthesis of 2-deoxy sugars via metal free deiodination reactions.Formula: C12H16O7 And the article contains the following content:
2-Deoxy-glycosides, in which the C-2 hydroxyl group is replaced with a hydrogen atom, are important motifs in numerous bioactive natural products and pharmaceutical mols. Herein, an improved dilauroyl peroxide-mediated radical deiodination reaction by using cyclohexane and Et acetate as co-solvent is reported. This is an environmentally benign protocol, which operates smoothly under mild conditions and allows efficient preparation of a series of 2-deoxy-glycosides in up to 98% yields. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Formula: C12H16O7
The Article related to solvent effect iodination deiodination dilauroyl peroxide catalyst glycoside preparation, deoxyglycoside preparation reductive deiodination lauroyl peroxide catalyst glycoside preparation and other aspects.Formula: C12H16O7
Referemce:
Ester – Wikipedia,
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