Wang, Yakun; Li, Yueyun; Lian, Mingming; Zhang, Jixia; Liu, Zhaomin; Tang, Xiaofei; Yin, Hang; Meng, Qingwei published an article in 2019, the title of the article was Asymmetric α-alkylation of cyclic β-keto esters and β-keto amides by phase-transfer catalysis.Computed Properties of 10472-24-9 And the article contains the following content:
Without employing any transition metal, a highly enantioselective α-alkylation of cyclic β-keto esters and β-keto amides has been realized by phase-transfer catalysis. This improved procedure is applicable to different kinds of bromides with cinchona derivatives and gives the corresponding products e.g., I and e.g., II, in excellent enantiopurities (up to 98% ee) and good yields (up to 98%). Moreover, the reaction was scalable and the phase-transfer catalyst was recyclable. This provided an alternative and competitive method to the asym. α-alkylation of β-dicarbonyl compounds The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Computed Properties of 10472-24-9
The Article related to indanone preparation enantioselective, keto ester alkyl bromide alkylation cinchona phase transfer catalyst, amide keto alkyl bromide alkylation cinchona phase transfer catalyst, tetralone preparation enantioselective and other aspects.Computed Properties of 10472-24-9
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics