Pastor-Nieto, Maria A.; Gatica-Ortega, Maria E.; Sanchez-Herreros, Consuelo; Vergara-Sanchez, Aranzazu; Martinez-Mariscal, Jaime; De Eusebio-Murillo, Esther published an article in 2021, the title of the article was Sensitization to benzyl salicylate and other allergens in patients with frontal fibrosing alopecia.Name: 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate And the article contains the following content:
Contact sensitization is frequent among patients with frontal fibrosing alopecia (FFA) (52%-76%). To evaluate the frequency of sensitization/photosensitization in an FFA population. A population of FFA patients were patch tested (Spanish Contact Dermatitis Research Group [GEIDAC] baseline; cosmetic and fragrance series), and photopatch tested (sunscreen series). Thirty-six patients (mean age: 64.6 years; 35/36: women) were studied. A history of dermatitis was recorded in 69.4% (frequently involving the face). Overall, 80.5% patients showed pos. patch-test reactions. The most frequently pos. allergens were nickel sulfate (25%), benzyl salicylate (22%), gallates (16.6%), propolis (16.6%), and limonene hydroperoxides (13.8%). Benzyl salicylate was likely relevant to the dermatitis (labeled on personal care products and most patients reporting clin. improvement with allergen avoidance). Patch tests with sunscreens showed pos. reactions to 11 materials (five patients). Photopatch tests were pos. in one case. We speculate a possible relationship between sensitization to benzyl salicylate and FFA. Hypothetically, the most likely explanation is that sensitization to benzyl salicylate involving FFA patients is a consequence of increased exposure to it. It is unclear whether allergen avoidance may impact the prognosis of alopecia. However, it seems to significantly improve the patients quality of life by lessening dermatitis and pruritus. The experimental process involved the reaction of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate(cas: 6197-30-4).Name: 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate
The Article related to benzyl salicylate allergen sensitization human frontal fibrosing alopecia, allergic contact dermatitis, benzyl salicylate (cas number 118-58-1), fragrance, frontal fibrosing alopecia, gallates, patch tests, photopatch tests, propolis, scarring alopecia, sunscreen and other aspects.Name: 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate
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