Frost, Grant B.; Mittelstaedt, Michaela N.; Douglas, Christopher J. published an article in 2019, the title of the article was Chemoselectivity for Alkene Cleavage by Palladium-Catalyzed Intramolecular Diazo Group Transfer from Azide to Alkene.Quality Control of Methyl N-Methylanthranilate And the article contains the following content:
A palladium-catalyzed intramol. azide to alkene DGT, which granted chemoselectivity over competing aziridination. The data supported a catalytic cycloreversion mechanism distinct from other known metal-catalyzed azide/alkene reactions: nitrenoid/metalloradical and (3+2) cycloadditions Kinetics experiments revealed an unusual mechanistic profile in which the catalyst was not operative during the rate-controlling step, rather, it was active during the product-determining step. Catalytic DGT was used to synthesize N-heterocyclic quinazolinones, a medicinally relevant structural core. On the competing aziridination and subsequent ring expansion to another N-heterocyclic core structure of interest, benzodiazepinones was also reported. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Quality Control of Methyl N-Methylanthranilate
The Article related to benzyl alkenyl phenyl carbamoyl azide preparation palladium catalyst chemoselective, benzo dihydroquinazolinone preparation, alkene cleavage, azides, cycloreversion, diazo group transfer, palladium and other aspects.Quality Control of Methyl N-Methylanthranilate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics