Song, Zhihua; Liu, Jinqiu; Zhang, Deyang; Wang, Yumeng; Lin, Wen; Bi, Yi; Wang, Hongbo; Arabi, Maryam; Li, Jinhua; Ma, Jiping; Wang, Yan; Chen, Lingxin published the artcile< Synthesis of C8F13-SiO2 stationary phase for chromatographic separation of highly polar compounds>, Application In Synthesis of 112-63-0, the main research area is perfluorooctyltriethoxysilanesilica stationary phase chromatog property.
Up to now, the chromatog. separation and anal. of highly polar compounds are still challenging because of low retention ability and selectivity of conventional stationary phases (SPs). Developing new SPs to achieve high-resolution and high-efficiency separation of polar compounds is of great importance for health and medicine, food safety, environmental protection, etc.. Herein, an influential multi-step modification strategy (modification with 1H,1H,2H,2H-perfluorooctyltriethoxysilane on the silica twice and end-capped with trimethylchlorosilane once) is introduced to prepare C8F13-SiO2 SP. The phys. properties of C8F13-SiO2 SP, including morphologies, pore structures and carbon content were fully characterized by various instrumental techniques. The packed HPLC column with C8F13-SiO2 SP exhibited high column efficiency, good peak shape (tailing factors for most analytes are between 0.9 and 1.3), and resolution for simultaneous separation of ginsenosides, sulfonamides, nucleosides, and benzoylurea insecticides (BUs); meanwhile, the retention mechanism of typical reversed-phase liquid chromatog. (RPLC) mode was observed A column efficiency of 30,220 plates/m for separation of ginsenoside Re was obtained. Furthermore, the resulting columns benefit from the advantages of supreme reproducibility, repeatability and stability. Importantly, the chromatog. properties (e.g. column efficiencies, chromatog. peak shapes, retention ability and resolution) of the C8F13-SiO2 SP for the polar analytes were superior to those of the com. SPs (including com. amino-modified silica SP, diol-modified silica SP and com. PFP-SiO2 SP). Thus, the C8F13-SiO2 SP is able to satisfy the strict requirements of highly polar compounds separation
Microchemical Journal published new progress about Particle size. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics