Pramanick, Pranab K.; Zhou, Zhibing; Hou, Zhenlin; Ao, Yufei; Yao, Bo published the artcile< Native amine-directed site-selective C(sp3)-H arylation of primary aliphatic amines with aryl iodides>, Reference of 2743-40-0, the main research area is aliphatic amine preparation aryl iodide regioselective arylation; aralkyl amine preparation.
A simple and efficient method for site-selective C(sp3)-H arylation of primary aliphatic amines by aryl iodides were established. In the presence of only 5 mol% Pd(OAc)2, a wide range of aliphatic amines including O-benzyl and O-silyl amino alcs. were arylated at γ- or δ-positions by aryl iodides containing a broad scope of functional groups. The synthetic application of this method had also been demonstrated by large-scale synthesis, the synthesis of a fingolimod analog and the conjugation with natural D-menthol and fluorescent 1,8-naphthalimide.
Chinese Chemical Letters published new progress about Aliphatic amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 2743-40-0 belongs to class esters-buliding-blocks, and the molecular formula is C8H18ClNO2, Reference of 2743-40-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics