Di Iorio, Nicola’s team published research in Tetrahedron in 2016-08-25 | 112-63-0

Tetrahedron published new progress about Atropisomers. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Di Iorio, Nicola; Champavert, Florian; Erice, Agostino; Righi, Paolo; Mazzanti, Andrea; Bencivenni, Giorgio published the artcile< Targeting remote axial chirality control of N-(2-tert-butylphenyl)succinimides by means of Michael addition type reactions>, Quality Control of 112-63-0, the main research area is remote axial chirality control Michael addition tertbutylphenylsuccinimide.

The efficient desymmetrization of N-(2-tert-butylphenyl)maleimides was realized by means of a Michael addition reaction of a series of carbon nucleophiles generating the corresponding axially chiral succinimides in high yields. The use of (DHQD)2Pyr as catalyst was fundamental to achieve the remote control of the stereogenic chiral axis with the concurrent construction of adjacent quaternary and tertiary stereocenters.

Tetrahedron published new progress about Atropisomers. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics