Zhulanov, Vladimir E.; Vigovskaya, Valeria A.; Dmitriev, Maksim V.; Silaichev, Pavel S.; Maslivets, Andrey N.; Rubin, Michael published the artcile< Dipyrazolodioxadiazocines as shelf-stable ""ready-to-use"" precursors for an in situ generation of enolate-iminium 1,4-dipoles: a straightforward atom-economical approach to pyrazolo[5,1-d][1,3,5]dioxazines>, HPLC of Formula: 94-02-0, the main research area is pyrazolodioxazine preparation atom economy; dipyrazolodioxadiazocine ketone heterocyclization insitu generated cyclic enolate iminium dipole.
An original, facile and highly efficient method for the in situ generation of cyclic enolate-iminium 1,4-dipoles via unique thermal decomposition of easily available dipyrazolodioxadiazocines was developed. Various substituted pyrazolo[5,1-d][1,3,5]dioxazines I [R1 = COOEt, PhCO, 4-MeC6H4CO, 4-ClC6H4CO; R2 = CO2Me, Ph; R3 = Me, Et; R4 = Et, t-Bu, n-Bu, i-Bu, Bn; R3R4 = (CH2)4, (CH2)5, (CH2)6, etc.] were prepared in high yields via unusual cycloconversion of dipyrazolodioxadiazocines in the presence of ketones. Furthermore, the developed method was 100% atom economical and proceeds under metal-, catalyst- and solvent-free conditions.
Organic & Biomolecular Chemistry published new progress about Atom economy. 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, HPLC of Formula: 94-02-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics