Li, Bing’s team published research in Tetrahedron Letters in 2013-06-12 | 30095-98-8

Tetrahedron Letters published new progress about Reductive cyclization. 30095-98-8 belongs to class esters-buliding-blocks, and the molecular formula is C9H9NO4, Formula: C9H9NO4.

Li, Bing; Williams, John D.; Peet, Norton P. published the artcile< Two concise total syntheses of the wasabi phytoalexin methyl 1-methoxyindole-3-carboxylate>, Formula: C9H9NO4, the main research area is nitrophenylacrylate preparation reductive cyclization; wasabi phytoalexin methoxyindolecarboxylate total synthesis.

Two new syntheses of the phytoalexin Me 1-methoxyindole-3-carboxylate (I) were developed that employ the same key intermediate. Me 2-(2-nitrophenyl)acrylate (II) was directly converted into I using modified Cadogan-Sundberg indole synthesis conditions with P(OMe)3. Acrylate II also underwent reductive cyclization with SnCl2 to give Me 1-hydroxyindole-3-carboxylate, which was methylated to produce I.

Tetrahedron Letters published new progress about Reductive cyclization. 30095-98-8 belongs to class esters-buliding-blocks, and the molecular formula is C9H9NO4, Formula: C9H9NO4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics