Hong, Chao; Yu, Shuling; Liu, Zhanxiang; Zhang, Yuhong published the artcile< Rh-Catalyzed Coupling of Acrylic/Benzoic Acids with α-Diazocarbonyl Compounds: An Alternative Route for α-Pyrones and Isocoumarins>, Formula: C11H12O3, the main research area is alkyl oxo aryl pyran carboxylate preparation; acrylic acid alpha diazocarbonyl compound coupling catalyst rhodium; isochromene alkyl oxo carboxylate preparation; aryl carboxylic acid alpha diazocarbonyl compound coupling catalyst rhodium.
A coupling of acrylic acids/benzoic acids with α-diazocarbonyl compounds had been realized by a combined catalytic system of rhodium catalyst and Zn(OAc)2 additive. The presence of Zn(OAc)2 obviously accelerates the C(sp2)-H activation and destructed the formation of carboxylic ester that was formed via a nucleophilic O-H insertion to metal carbenoid. The procedure featured mild reaction conditions and broad substrate scope, providing a straightforward approach to the synthesis of α-pyrones I [R1 = Me, Ph, Bn, etc.; R2 = H, Me, Ph; R1R2 = (CH2)4; R3 = Me, Et, allyl, t-Bu, R4 = Me, Et, Ph, etc.] and isocoumarins II [R = H, 8-Me, 8-Me-6-MeO, etc.] without the transformation of carboxylic acids to the corresponding amides.
Organic Letters published new progress about 1,3-Dicarbonyl compounds Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Formula: C11H12O3.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics