de Ancos, Begona; Maestro, M. Carmen; Martin, M. Rosario; Mateo, Ana I. published the artcile< Reactions of pyrrolidine enamines of cyclic and acyclic 3,4-dioxobutanoic acid derivatives with dimethyl acetylenedicarboxylate. A new case of atropisomerism>, Recommanded Product: Methyl 4,4-dimethoxy-3-oxobutanoate, the main research area is pyrrolidine enamine reaction acetylenedicarboxylate atropisomerism.
Reaction conditions and structure of the starting enamines (cyclic or open-chain) determine greatly the final products of the title reactions. Whereas in benzene and acetonitrile, MeO2CCCCO2Me and pyrrolidinylbutanoate I give a mixture of the diastereoisomeric dienamines II, in methanol I affords pyrrolizine III. Enaminofuranones IV (R = Me, menthyl, R1 = H) furnish the corresponding “”Michael adducts”” (E)- and (Z)-IV and V but fail to yield pyrrolizines.
Tetrahedron published new progress about Atropisomers. 60705-25-1 belongs to class esters-buliding-blocks, and the molecular formula is C7H12O5, Recommanded Product: Methyl 4,4-dimethoxy-3-oxobutanoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics