Das, Anindita; Theato, Patrick published the artcile< Multifaceted Synthetic Route to Functional Polyacrylates by Transesterification of Poly(pentafluorophenyl acrylates)>, HPLC of Formula: 71195-85-2, the main research area is polyacrylate transesterification polypentafluorophenyl acrylate.
Synthesis of functional polyacrylates by 4-dimethylaminopyridine (DMAP) catalyzed trans-esterification of poly(pentafluorophenyl acrylate) (polyPFPA) is reported. High fidelity and versatility of this strategy was exemplified by near quant. conversion with diverse functional alcs. (primary, secondary as well as phenolic) featuring reactive groups like alkene, alkyne or acrylate, enabling further sequential functionalization using click chem. Co-integrating an equimolar mixture of allyl and propargyl alc. produced an orthogonally clickable copolymer by thiol-ene and 1,3-cycloaddition reaction. Base catalyzed ester exchange allowed installation of acid labile Boc-L-serine to create amino acid pendent polymer keeping both NH2- and COOH-group free, thereby providing a facile route toward zwitterionic polymers. Reaction with 2-dimethylaminoethanol conferred dual pH and CO2 responsive polymers from the same reactive precursor. The synthetic strategy was further extended to attach alcs. obtained from natural resources such as geraniol, L-lactic acid or sesamol to engineer new renewable polymers. Even a graft copolymer with very high (93%) grafting d. could be achieved utilizing PEG350-OH. The trans-esterification was found to be highly selective for primary alcs. over secondary alcs. and also to the activated PFP-ester over a normal ester such as poly(Me acrylate). Using such selectivity, fluorescently tagged polymer could be synthesized by replacing only the PFP-ester of a poly(Me acrylate-co-PFPA) with 1-pyrenemethanol. Further, PFPA was polymerized with 2.0 mol % diacrylate to produce a cross-linked gel network. The PFP-ester groups of the cross-linked gel could be quant. replaced with Boc-L-serine, which upon deprotection of the Boc group resulted in a novel zwitterionic hydrogel exhibiting pH-dependent swelling properties. Time-dependent FTIR experiment suggested fast kinetics of the reaction, making this synthetic route practically applicable for postpolymn. modification. Mechanistic investigation exposed involvement of both DMAP and the nucleophilic solvent N,N-dimethylformamide (DMF) in catalyzing the reaction. This also explains the reason as to why near quant. conversion was achieved in DMF and not in the non-nucleophilic solvent 1,4-dioxane.
Macromolecules (Washington, DC, United States) published new progress about Acrylic polymers Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, HPLC of Formula: 71195-85-2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics