Biswas, Kallolmay; Kumar, Arvind; Das Sarma, Koushik published the artcile< One-Pot High-Throughput Synthesis of a 160-Membered Library of Methyl 3,5-Diaryl-isoxazoline-5-carboxylate Pharmacophores by a 2·2·2-Component Reaction>, Name: Methyl 2-(2-nitrophenyl)acetate, the main research area is aryl aldehyde arylacetate high throughput multicomponent reaction; oxime arylacrylate intermediate sequential two component reaction; diaryloxazoline carboxylate library one pot preparation.
A simple and efficient methodol. has been developed for the synthesis of Me 3,5-diaryl-isoxazoline-5-carboxylates in a high-throughput fashion from aryl aldehydes and Me arylacetates. This was accomplished in one-pot by a sequence of three 2-component reactions steps (2·2·2-CR), through oxime and α-arylacrylate intermediates, whereby compounds were obtained in overall 30-66% isolated yields. The functional group diversity was established by synthesizing a 160-membered library.
ACS Combinatorial Science published new progress about 1,3-Dipolar cycloaddition reaction. 30095-98-8 belongs to class esters-buliding-blocks, and the molecular formula is C9H9NO4, Name: Methyl 2-(2-nitrophenyl)acetate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics